Low Dose Naltrexone (LDN) for Inflammation, Autoimmune Symptoms, Sleep, and Energy
Initial 90 Day Supply: $249
Telemedicine consult + personalized dosing included.
CalibrateRx™ is a clinically guided Low Dose Naltrexone (LDN) program designed to support individuals experiencing autoimmune symptoms, chronic inflammation, long COVID effects, pain, poor sleep, brain fog, and persistent low energy. Our precision dosed LDN formulation helps modulate immune activity, calm inflammatory pathways, and support healthier nervous system signaling—promoting more restorative sleep, improved cognitive function, and steadier day to day resilience.
Why CalibrateRx™ Matters
Low Dose Naltrexone (LDN) is increasingly used to support individuals struggling with immune dysregulation, chronic inflammation, nerve pain, and post viral symptoms. By modulating inflammatory signaling and calming overactive microglia, CalibrateRx™ helps support:
• Immune system modulation
• Reduced chronic inflammation
• Healthier pain & neuro immune signaling
• Improved sleep quality
• More stable mood
• Support for autoimmune related symptoms
• Nervous system calm and resilience
• Improved daily energy & cognitive clarity
How LDN Works
Endorphin Upregulation:
LDN temporarily blocks opioid receptors overnight, prompting increased endorphin production—supporting immune balance, inflammation control, mood, and pain perception.
Microglial Modulation:
LDN helps regulate overactive microglia, supporting improvements in brain fog, fatigue, mood disturbances, and chronic pain.
Dual Action Neuro Immune Support:
LDN works on both immune and neurological pathways to help the body move toward better regulation and long term resilience.
What’s Included
• 90 day supply of compounded Low Dose Naltrexone
• Telemedicine consultation
• Personalized dosing plan
• Ongoing clinical oversight
• Priority refill processing
What to Expect
Weeks 1–3: inflammation begins to ease, deeper sleep, steadier mood
Weeks 4–8: fewer flare ups, clearer focus, more reliable energy
Weeks 8+: improved resilience, reduced lingering symptoms, calmer nervous system
Who Should Not Take CalibrateRx™
Not appropriate for individuals using opioid medications, those with certain liver conditions, pregnancy/breastfeeding, or those advised against LDN by their clinician.
Compounding & Regulatory Disclosure
CalibrateRx™ is a custom compounded prescription therapy prepared by a licensed compounding pharmacy in Florida.
It is not FDA approved as a commercial product; however, all ingredients are sourced from FDA registered suppliers.
CalibrateRx™ is dispensed only under provider supervision and must be used as directed following a telehealth consultation. Your medication will arrive in standard pharmacy packaging and will not display the CalibrateRx™ or NightingaleRx™ name on the label.
About Nightingale Rx™
Nightingale Rx™ is a concierge wellness platform that connects licensed medical providers with patients seeking personalized, clinically guided care.
Nightingale Rx™ does not manufacture, sell, or dispense compounded medications.
All therapies—including CalibrateRx™—are prescribed, managed, and overseen solely by independent clinicians in accordance with applicable laws and clinical judgment.
🌸 CalibrateRx™
Precision support for immune balance, inflammation relief, and whole body resilience.